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Evidence Synthesis

Expert-led, technology-enhanced evidence synthesis

Evidence synthesis is foundational to healthcare decision-making and product development. Our dedicated evidence synthesis teams, supported by advanced technology, provide an agile, dynamic, and strategically driven solution.

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Our biopharma evidence synthesis services include:

  • Systematic literature reviews (SLRs)
  • Targeted literature reviews (TLRs)
  • Landscape reviews
  • Evidence mapping
  • Meta-analyses
  • Meta-regression
  • Indirect treatment comparisons, including NMA and MAIC
  • Simulated treatment comparisons

Leverage the evidence base

Our multidisciplinary evidence synthesis teams offer expertise across RWE, HEOR, biostatistics, and access and pricing, providing the evidence you need within the most demanding of timelines and allowing you to focus on strategic interpretation.

We provide qualitative and quantitative evidence synthesis to support varying requirements, including dossier development, internal strategy support, gap analysis, modelling inputs, publication, HTA/payer/reimbursement submissions, regulatory submissions, rapid reviews, and more.

  • Ongoing reviews for competitor intelligence: Efficient regular updates to keep you ahead of the emerging evidence base.
  • Rapid turnarounds: Answering urgent scientific questions within hours, and meeting the tightest of deadlines (e.g. mid-appraisal rejections).
  • Enhanced evidence synthesis: Faster and more comprehensive systematic/targeted literature reviews, landscape analysis, and regulatory and HTA response generation.
Ask us about evidence synthesis

Faster, transparent, high-quality systematic reviews

Our dedicated evidence synthesis teams are supported by EVID AI, an AI-powered online database of literature-based evidence which employs semantic understanding to extract transparent and exportable data from published literature and identifies the context from which it has been extracted.

How does it work?


data points of evidence curated


faster than human searches using PubMed


more articles found and 15x fewer irrelevant ones
fit for purpose expertise team
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Flexible Integrated Teams (FIT)

Making fit-for-purpose expertise the new standard: Our team becomes your team

Our biopharma evidence synthesis services can be offered as part of an optional FIT engagement. These flexible partnerships provides dedicated, cross-functional teams that integrate seamlessly within your own to fill experience gaps or supplement existing resources.

The size and composition of your team can gradually evolve or pivot quickly to meet your changing needs, all without the costly delays involved in adjusting a statement of work.

A trusted extension of your organization, our team becomes your team.

Learn more
Evidence Synthesis Case Study

Targeted literature review for lung cancer RWE to support HTA submission

There was a lack of literature and randomized controlled trial data evaluating to the post-surgery follow-up care among early non-small cell lung cancer (eNSCLC) patients who experienced locoregional recurrence. Client required literature review expertise to assess current state of the eNSCLC outcomes.

Genesis Research Group collaborated with the client to design and conduct a targeted literature review (TLR) to analyze survival and treatment patterns outcomes in observational studies.

Ultimately, the data found was used to support inputs for economic models and health technology assessment (HTA) submission.

Download full case study

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